Author

Sean F. Monaghan

Brown UniversityORCID 0000-0003-1490-3043Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alger M. FredericksiD· 2 shared Alfred AyalaiD· 1 shared Allison J. TaggartiD· 1 shared Anastasia WelchiD· 1 shared Chaorui DuaniD· 1 shared Chien‐Ling LiniD· 1 shared Cory BowersiD· 1 shared Daxing GaoiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Alger M. FredericksORCID

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2 papers

Recent·Most cited

Molecular BiologyThe Journal of Experimental MedicinePeer-reviewedJan 15, 2026

Elevated levels of intracellular RNA lariats suppress the antiviral response

Chaorui Duan, Luke Buerer, Cory Bowers…·William Guy Fairbrother

The paper shows that accumulation of intracellular RNA lariats in DBR1-null cells reduces antiviral response by desensitizing dsRNA sensors.

2 citations

𝕏 PostBluesky

GenomicsbioRxivPreprintJan 25, 2021

Pre-mRNA processing entropy in a mouse model of trauma

Maximilian S. Jentzsch, Alger M. Fredericks, Jason T. Machan…·Sean F. Monaghan

This study uses RNA sequencing to analyze pre-mRNA processing entropy in a mouse trauma model, finding that trauma alters global entropy and correlates with survival.

DOI 10.1101/2021.01.25.428080

mousebulk RNA-seq

𝕏 PostBluesky