Author

Jason T. Machan

Brown UniversityORCID 0000-0003-2048-4914Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alfred AyalaiD· 1 shared Alger M. FredericksiD· 1 shared Craig T. LefortiD· 1 shared Debra Ellisor· 1 shared Diane Hoffman–KimiD· 1 shared Katherine XiongiD· 1 shared Kimberly A. Seymour· 1 shared Kristina D. HinmaniD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperGenomics

Alfred AyalaORCID

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3 papers

Recent·Most cited

ImmunologyJournal of Leukocyte BiologyPeer-reviewedFeb 3, 2026

Neutrophil progenitor cell therapy rescues host defense against Staphylococcus aureus in murine chronic granulomatous disease

Kristina D. Hinman, Jason T. Machan, Craig T. Lefort

DOI 10.1093/jleuko/qiag020

mouseexperimental assay

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GenomicsbioRxivPreprintJan 25, 2021

Pre-mRNA processing entropy in a mouse model of trauma

Maximilian S. Jentzsch, Alger M. Fredericks, Jason T. Machan…·Sean F. Monaghan

This study uses RNA sequencing to analyze pre-mRNA processing entropy in a mouse trauma model, finding that trauma alters global entropy and correlates with survival.

DOI 10.1101/2021.01.25.428080

mousebulk RNA-seq

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NeurosciencebioRxivPreprintFeb 5, 2017

Quantitative Analysis of Dopamine Neuron Subtypes Generated from Mouse Embryonic Stem Cells

Yu‐Ting L. Dingle, Katherine Xiong, Jason T. Machan…·Mark Zervas

The paper quantifies DA neuron subtypes generated from mouse ESCs and finds higher production of calbindin+ subtype compared to calretinin+ subtype, with no effect from SHH and FGF8.

1 citation

mousebulk RNA-seq

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