NeuroscienceCell GenomicsPeer-reviewed
Single-nucleus transcriptome atlas of orbitofrontal cortex in amyotrophic lateral sclerosis with a deep learning-based decoding of alternative polyadenylation mechanisms
Paul M. McKeever, Aiden M. Sababi, Raghav Sharma…·Janice Robertson
The paper constructs a single-nucleus transcriptome atlas of the orbitofrontal cortex in ALS and identifies cell-type-specific transcriptional changes, introducing a deep learning model to analyze alternative polyadenylation.