MicrobiologybioRxivPreprint
Influenza A virus transcription generates capped cRNAs that activate RIG-I
Elizaveta Elshina, Emmanuelle M. Pitré, Marisa Mendes…·Aartjan J.W. te Velthuis
This study identifies a novel IAV RNA species, capped complementary RNAs (ccRNAs), which hybridize with viral RNA to activate RIG-I, revealing an alternative mechanism for innate immune activation during IAV infection.
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