NeurosciencebioRxivPreprint
Infection-induced epilepsy is caused by increased expression of chondroitin sulfate proteoglycans in hippocampus and amygdala
Dipan C. Patel, Nathaniel A. Swift, Bhanu P. Tewari…·Harald W. Sontheimer
This study identifies increased chondroitin sulfate proteoglycans (CSPGs) in the hippocampus and amygdala as a cause of infection-induced epilepsy, showing their role in neuronal hyperexcitability and potential as a therapeutic target.
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