Author

Matthieu D. Lavigne

FORTH Institute of Molecular Biology and BiotechnologyORCID 0000-0003-1543-8745Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Anastasios LiakosiD· 1 shared Celia Pilar Martinez‐JimeneziD· 1 shared Dimitris Botskaris· 1 shared Dimitris KonstantopoulosiD· 1 shared Electra Tsaglioti· 1 shared Elena DeligianniiD· 1 shared Haroula Kontaki· 1 shared Iannis TalianidisiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperMolecular Biology

Anastasios LiakosORCID

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3 papers

Recent·Most cited

Cell BiologyiSciencePeer-reviewedJul 9, 2026

Setdb1 regulates proper differentiation of adult intestinal stem cells via restraining permissive chromatin structure and transcriptional variability

Ioanna Peraki, Liwei Zhang, Dimitris Botskaris…·Iannis Talianidis

This study shows that Setdb1 regulates intestinal stem cell differentiation by controlling chromatin accessibility and transcriptional variability in adult stem cells.

DOI 10.1016/j.isci.2026.116731

mouseChIP-seq

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NeuroscienceAlzheimer s Research & TherapyPeer-reviewedFeb 20, 2026

p75 Neurotrophin Receptor Shapes the Dynamics of Adult Hippocampal Neurogenesis in Alzheimer's Disease

Maria Anna Papadopoulou, Konstantina Chanoumidou, Maria Peteinareli…·Ioannis Charalampopoulos

This study shows that p75NTR regulates adult hippocampal neurogenesis in Alzheimer's disease, with its deletion worsening neurogenic deficits in mouse models and human iPSC-derived cells.

DOI 10.1186/s13195-026-01989-7

mouseexperimental assay

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Molecular BiologyNature CommunicationsPeer-reviewedFeb 14, 2020

Continuous transcription initiation guarantees robust repair of transcribed genes and regulatory regions in response to DNA damage

Anastasios Liakos, Dimitris Konstantopoulos, Matthieu D. Lavigne, Maria I. Fousteri

The paper shows that continuous transcription initiation after DNA damage enhances repair of genes and regulatory regions by maintaining Pol II pause-release dynamics and chromatin accessibility.

28 citations

humanbulk RNA-seq

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