Christophe Michel Raynaud

This study shows SLFN11 enhances cisplatin sensitivity in pediatric cancers by modulating stress-response and survival pathways through epigenetic regulation and functional assays.

This study identifies immune subtypes of colorectal cancer using methylation patterns, linking them to distinct clinical outcomes and immune programs.

This study shows mitochondrial dysfunction and oxidative stress occur before neuronal loss in DRPLA patient-derived neurons, and phenylbutyrate treatment improves survival.

This study investigates how MUC2 expression affects immune infiltration in colorectal cancer using in vitro models and CRISPR knockout, finding that MUC2 loss increases immune infiltration only in HT-29 cells.