Author

Ayesha Jabeen

Sidra Medical and Research CenterORCID 0009-0000-2261-5055Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christophe Michel RaynaudiD· 2 shared Eiman I. AhmediD· 2 shared Shimaa SherifiD· 2 shared W. R. L. HendrickxiD· 2 shared Ahmad Al‐ShaibiiD· 1 shared Apryl SancheziD· 1 shared Ayman SalehiD· 1 shared Bernice LoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Christophe Michel RaynaudORCID

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2 papers

Recent·Most cited

Cancer BiologyBritish Journal of CancerPeer-reviewedSep 2, 2026

SLFN11 Enhances Cisplatin Sensitivity in Pediatric Cancer via Activation of Stress-Response and Suppression of Survival Pathways

Ayesha Jabeen, Dina Awartani, Shimaa Sherif…·Christophe Michel Raynaud

This study shows SLFN11 enhances cisplatin sensitivity in pediatric cancers by modulating stress-response and survival pathways through epigenetic regulation and functional assays.

DOI 10.1038/s41416-026-03571-2

humanbulk RNA-seq

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Cancer BiologyFrontiers in ImmunologyPeer-reviewedJan 24, 2025

MUC2 Expression Modulates Immune Infiltration in Colorectal Cancer

Christophe Michel Raynaud, Ayesha Jabeen, Eiman I. Ahmed…·W. R. L. Hendrickx

This study investigates how MUC2 expression affects immune infiltration in colorectal cancer using in vitro models and CRISPR knockout, finding that MUC2 loss increases immune infiltration only in HT-29 cells.

11 citations

humangenetic perturbation / CRISPR

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