Author
The Netherlands Cancer InstituteORCID 0000-0003-1555-587XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Marius Messemaker, Bjørn P. Y. Kwee, Živa Moravec…·Ton N. Schumacher
The paper develops a validated TCR-pMHC database (TCRvdb) by assessing VDJdb entries with a high-throughput platform, finding only 50% of claims are functionally confirmed.
Marius Messemaker, Connor A. Richterich, Jule Wenner…·Ton N. Schumacher
PAIR-Scan identifies potent TCR-neoantigen pairs from tumor samples through library-on-library screening, enabling efficient analysis of T cell reactivity.
Kaspar Bresser, Žan Hozjan, Nila H. Servaas…·Monika C. Wolkers
The paper identifies proteomic regulators of T cell functionality in cancer using proteomic and transcriptomic profiling of tumor-infiltrating T cells.
Bjørn P. Y. Kwee, Marius Messemaker, Eric Marcus…·Ton N. Schumacher
STAPLER is a transformer model that predicts TCR-pMHC specificity by learning from TCR and peptide sequences, outperforming existing methods in antigen recognition prediction.