Kaspar Bresser

The paper identifies proteomic regulators of T cell functionality in cancer using proteomic and transcriptomic profiling of tumor-infiltrating T cells.

The paper identifies RNA binding proteins and cis-regulatory elements that control translation in human effector T cells through multi-omics and machine learning analysis.

This study identifies an early mTOR-dependent window during human T cell activation that programs cytotoxic fate or memory-like state, with transient inhibition promoting memory while preserving effector functions.

The paper maps dynamic RNA-binding proteins in human effector T cells and identifies TUT1 and SF3A1 as regulators of differentiation and cytotoxicity.

This study identifies a novel mTOR-dependent mechanism regulating cytokine production in T cells through 3UTR AU-rich elements and DDX21 binding.