Author

Layla Ghaffari

Thomas Jefferson UniversityORCID 0000-0003-1573-7745Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron R. HaeusleriD· 1 shared Ashley V. BoehringeriD· 1 shared Catherine A. CollinsiD· 1 shared Davide TrottiiD· 1 shared Elizabeth M.H. TankiD· 1 shared Emile S. PinarbasiiD· 1 shared Emily M. Welebob· 1 shared Erik M. UllianiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Aaron R. HaeuslerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeuroscienceAmerican Journal of Physiology-Cell PhysiologyPeer-reviewedAug 28, 2025

Neuronal Activity-Dependent Gene Dysregulation in C9orf72 i3 Neuronal Models of ALS/FTD Pathogenesis

Layla Ghaffari, Emily M. Welebob, Sarah E. Bond Newton…·Aaron R. Haeusler

This study shows that C9orf72 repeat expansion neurons have altered transcriptomes under different stimulation conditions, revealing activity-dependent gene dysregulation in ALS/FTD.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceJournal of Clinical InvestigationPeer-reviewedJun 24, 2025

Nemo-like kinase disrupts nuclear import and drives TDP43 mislocalization in ALS

Michael E. Bekier, Emile S. Pinarbasi, Gopinath Krishnan…·Sami J. Barmada

This study shows NLK disrupts nuclear import, causing TDP43 mislocalization in ALS, and suggests NLK as a therapeutic target.

2 citations

humanexperimental assay

𝕏 PostBluesky