Author

Kazuhiko Sakaguchi

Kobe UniversityORCID 0000-0003-1577-2401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

Shinya KurodaiD· 2 shared Wataru OgawaiD· 2 shared Hikaru SugimotoiD· 1 shared Hiroyuki KubotaiD· 1 shared Hisako Komada· 1 shared Kaoru Ohashi· 1 shared Ken‐ichi HironakaiD· 1 shared Masashi FujiiiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersSystems Biology

Shinya KurodaORCID

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2 papers

Recent·Most cited

Systems BiologyThe Journal of Clinical Endocrinology & MetabolismPeer-reviewedJul 5, 2023

DI/cle, a Measure Consisting of Insulin Sensitivity, Secretion, and Clearance, Captures Diabetic States

Hikaru Sugimoto, Ken‐ichi Hironaka, Tomoko Yamada…·Shinya Kuroda

The paper introduces DI/cle, a new index combining insulin sensitivity, secretion, and clearance, showing it is impaired in T2DM but not in IGT.

8 citations

humanstatistical model

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Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedMar 8, 2018

Bidirectional Changes Of Hepatic And Peripheral Insulin Clearance Characterize Abnormal Temporal Patterns Of Serum Insulin Concentration In Diabetic Subjects

Kaoru Ohashi, Masashi Fujii, Shinsuke Uda…·Shinya Kuroda

The paper develops a mathematical model to show that bidirectional changes in hepatic and peripheral insulin clearance explain abnormal serum insulin concentration patterns in diabetic subjects.

26 citations

humanstatistical model

𝕏 PostBluesky