Author

Wataru Ogawa

Kobe UniversityORCID 0000-0002-0432-4366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Kazuhiko SakaguchiiD· 2 shared Shinya KurodaiD· 2 shared An Liyuan· 1 shared Christopher K. GlassiD· 1 shared Gérard KarsentyiD· 1 shared Hikaru SugimotoiD· 1 shared Hiroyuki KubotaiD· 1 shared Hisako Komada· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersSystems Biology

Kazuhiko SakaguchiORCID

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3 papers

Recent·Most cited

A skeletal muscle-sympathetic nerve-intestine network underlies muscle inflammation and atrophy induced by immobilization

Yu Hirata, Kazuhiro Nomura, Kaori Hozumi, Kenji Sugawara, Yusei Hosokawa, Kana Uchiyama, Tomoya Inoue, Tomoko Nishigaki, An Liyuan, Serika Yamada, Yutaro Miyatake, Takahiro Niikura, Tomoaki Fukui, Keisuke Oe, Ryosuke Kuroda, , Wataru Ogawa

This study identifies a muscle-sympathetic nerve-intestine network that drives inflammation and atrophy in immobilized muscles, showing that intestinal inflammation contributes to muscle damage.

bioRxiv · Feb 25, 2025 · PreprintMolecular Biology

DI/cle, a Measure Consisting of Insulin Sensitivity, Secretion, and Clearance, Captures Diabetic States

Hikaru Sugimoto, Ken‐ichi Hironaka, Tomoko Yamada, Kazuhiko Sakaguchi, Wataru Ogawa, Shinya Kuroda

The paper introduces DI/cle, a new index combining insulin sensitivity, secretion, and clearance, showing it is impaired in T2DM but not in IGT.

The Journal of Clinical Endocrinology & Metabolism · Jul 5, 2023Peer-reviewedSystems Biology

Bidirectional Changes Of Hepatic And Peripheral Insulin Clearance Characterize Abnormal Temporal Patterns Of Serum Insulin Concentration In Diabetic Subjects

Kaoru Ohashi, Masashi Fujii, Shinsuke Uda, Hiroyuki Kubota, Hisako Komada, Kazuhiko Sakaguchi, Wataru Ogawa, Shinya Kuroda

The paper develops a mathematical model to show that bidirectional changes in hepatic and peripheral insulin clearance explain abnormal serum insulin concentration patterns in diabetic subjects.

npj Systems Biology and Applications · Mar 8, 2018Peer-reviewedSystems Biology