Author

Sharie Keanne C. Ganchua

University of PittsburghORCID 0000-0003-1577-5055Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Organism:non-human primate· 2 Assay:clinical cohort / trial· 1

Frequent Co-Authors

Douaa MugahidiD· 2 shared JoAnne L. FlynniD· 2 shared Michael C. ChaoiD· 2 shared Pauline A MaielloiD· 2 shared Philana Ling LiniD· 2 shared Sarah M. FortuneiD· 2 shared Alex K. ShalekiD· 1 shared Bonnie BergeriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Douaa MugahidORCID

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2 papers

Recent·Most cited

ImmunologyImmunityPeer-reviewedAug 29, 2024

CD4+ T cells are homeostatic regulators during Mtb reinfection

Joshua D. Bromley, Sharie Keanne C. Ganchua, Sarah K. Nyquist…·JoAnne L. Flynn

The paper shows that CD4+ T cells reduce inflammation and disease severity during Mtb reinfection by reprogramming CD8+ T cells and innate immune cells.

43 citationstop 1%

non-human primateflow cytometry

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MicrobiologyInfection and ImmunityPeer-reviewedMar 22, 2024

Antibiotic treatment does not abrogate protection against Mycobacterium tuberculosis reinfection

Sharie Keanne C. Ganchua, Pauline A Maiello, Michael C. Chao…·JoAnne L. Flynn

This study shows antibiotic treatment after primary Mtb infection reduces lung inflammation but does not eliminate protection against reinfection in macaques.

13 citations

non-human primateflow cytometry

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