Author

Marco Dal Molin

Johns Hopkins UniversityORCID 0000-0003-1581-3576Unclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

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Alexander H. PearlmaniD· 1 shared Bert VogelsteiniD· 1 shared Brian J. MogiD· 1 shared Bum Seok LeeiD· 1 shared Chetan BettegowdaiD· 1 shared Denis WirtziD· 1 shared Drew M. PardolliD· 1 shared Evangeline Watson· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperSynthetic Biology

Alexander H. PearlmanORCID

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1 paper

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Synthetic BiologybioRxivPreprintMay 24, 2026

Spatial Regulation of CAR Signaling Enables Logic-Gated Activity

Tushar D. Nichakawade, Brian J. Mog, Alexander H. Pearlman…·Kenneth W. Kinzler

The paper designs an AND-gated CAR T cell receptor called MANTIS that uses extracellular size differences to spatially regulate signaling for precise antigen recognition.

DOI 10.64898/2026.05.22.726983

experimental assay

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