Author

Nynke Marije Hettema

Delft University of TechnologyORCID 0000-0003-1592-1710Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:fluorescence / live-cell microscopy· 1 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

Liedewij LaaniD· 2 shared Alejandro Castañeda Garcia· 1 shared Benjamin SpitzbarthiD· 1 shared Bing Xu· 1 shared Chun-Ting Cho· 1 shared Cristiano GlessiiD· 1 shared Daan BrinksiD· 1 shared Frank van Opstal· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Liedewij LaanORCID

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2 papers

Recent·Most cited

BiochemistryACS Synthetic BiologyPeer-reviewedMay 13, 2026

Sortase A-mediated farnesylation of Cdc42 in vitro

Sophie Tschirpke, Nynke Marije Hettema, Benjamin Spitzbarth…·Liedewij Laan

This paper introduces a Sortase A-based method to farnesylate Cdc42 in vitro, enabling efficient and reproducible prenylation for biochemical studies.

3 citations

yeastproteomics

𝕏 PostBluesky

BiophysicsAdvanced MaterialsPeer-reviewedApr 16, 2026

Plasmonic Enhancement of Protein Function

Marco Locarno, Qiangrui Dong, Marco Post…·Daan Brinks

This study demonstrates plasmonic enhancement of protein function in living cells by coupling designed nanoparticles to Archaerhodopsin proteins, increasing fluorescence and response speed.

2 citations

fluorescence / live-cell microscopyexperimental assay

𝕏 PostBluesky