Author

Rico Hagelaar

Oncode InstituteORCID 0000-0003-1622-6293Unclaimed ORCID profile · follow to get notified of new preprints

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Rico Hagelaar1 paper

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:clustering· 1 Research Focus:phylogenetics / evolution· 1 Approach:simulation· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Laurianne TrabutiD· 2 shared Lucca L. M. DerksiD· 2 shared Mark VerheuliD· 2 shared Markus J. van RoosmaleniD· 2 shared Ruben van BoxteliD· 2 shared Alexander R. BlackwelliD· 1 shared Alexander S. SteemersiD· 1 shared Andrea GuarracinoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenomics

Laurianne TrabutORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintOct 30, 2026

Somatic variant detection using an individual-specific pangenome reference: a case study of a pediatric acute myeloid leukemia patient

Elizaveta Kulaeva, Eline J.M. Bertrums, Markus J. van Roosmalen…·Andrea Guarracino

This study evaluates the impact of an individual-specific pangenome on somatic variant calling in a pediatric AML patient, finding reduced false positives and altered phylogenetic branching.

DOI 10.64898/2026.10.27.756267

humanwhole-genome sequencing

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Cancer BiologyNature CommunicationsPeer-reviewedJun 8, 2026

Single-cell whole-genome sequencing reveals convergent evolution in Burkitt lymphoma

Alexander S. Steemers, Markus J. van Roosmalen, Rico Hagelaar…·Ruben van Boxtel

This study uses single-cell whole-genome sequencing to show that Burkitt lymphoma develops through convergent evolution, with early genetic diversity and accelerated mutation accumulation.

1 citation

humanwhole-genome sequencing

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