GenomicsProceedings of the National Academy of SciencesPeer-reviewed
Multi-omics profiling of mouse polycystic kidney disease progression at a single cell resolution
Yoshiharu Muto, Yasuhiro Yoshimura, Hao Wu…·Benjamin D. Humphreys
This study uses single-nucleus multi-omics to analyze mouse PKD progression, identifying cell-type-specific gene and epigenetic changes and conserved regulatory pathways between mouse and human.