Nathaniel Lim

The paper identifies small molecules that enhance stem cell differentiation into definitive endoderm, reducing costs by 90% through a drug repurposing approach.

This study evaluates the reproducibility of the Connectivity Map (CMap) for drug repositioning and finds limited reliability between CMap versions and low differential expression consistency.

The paper curates over 10,000 transcriptomic datasets to improve data reuse by standardizing metadata, processing, and annotations.