Author

Izortze Santín

University of the Basque CountryORCID 0000-0003-1651-6776Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Ainara Castellanos–RubioiD· 2 shared Ane Olazagoitia‐GarmendiaiD· 2 shared Henar Rojas MárqueziD· 2 shared Jon MentxakaiD· 2 shared Koldo García‐EtxebarriaiD· 2 shared Luis Manuel MendozaiD· 2 shared Aïsha CallebautiD· 1 shared Alain Huerta Madrigal· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersImmunology

Ainara Castellanos–RubioORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 2, 2025

Long non-coding RNAs as a novel source of beta cell autoantigens in type 1 diabetes

Jon Mentxaka, Aïsha Callebaut, Koldo García‐Etxebarria…·Izortze Santín

This study identifies lncRNA-derived peptides that act as autoantigens in type 1 diabetes by activating CD4+ T cells through HLA-II restricted epitopes.

DOI 10.64898/2025.12.01.691527

humanproteomics

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Molecular BiologyAdvanced SciencePeer-reviewedJan 25, 2024

m6A methylated long noncoding RNA regulates proinflammatory response emerging as novel target for IBD

Ane Olazagoitia‐Garmendia, Henar Rojas Márquez, Maialen Sebastian‐delaCruz…·Ainara Castellanos–Rubio

The paper identifies LOC339803 lncRNA as a mediator of intestinal inflammation through m6A methylation and YTHDC1 interaction, suggesting it as a potential therapeutic target for IBD.

15 citations

humanlong-read sequencing

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GeneticsAdvanced SciencePeer-reviewedJun 29, 2023

The type 1 diabetes-associated lncRNA ARGI participates in virus-induced pancreatic beta cell inflammation.

Itziar González‐Moro, Koldo García‐Etxebarria, Luis Manuel Mendoza…·Izortze Santín

This study identifies the lncRNA ARGI as a mediator of virus-induced inflammation in pancreatic beta cells linked to type 1 diabetes through allele-specific transcriptional activation.

9 citations

humanDNA methylation

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