Author

Ainara Castellanos–Rubio

IkerbasqueORCID 0000-0003-3192-9544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Ane Olazagoitia‐GarmendiaiD· 2 shared Henar Rojas MárqueziD· 2 shared Izortze SantíniD· 2 shared Aïsha CallebautiD· 1 shared Alain Huerta Madrigal· 1 shared Aloña Agirre LizasoiD· 1 shared Anne Ochoa· 1 shared Anthony R. Jones· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Ane Olazagoitia‐GarmendiaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Long non-coding RNAs as a novel source of beta cell autoantigens in type 1 diabetes

Jon Mentxaka, Aïsha Callebaut, Koldo García‐Etxebarria, Leire Bergara-Muguruza, Izei Pascual-González, Anthony R. Jones, Kedi Li, Henar Rojas Márquez, Ainara Castellanos–Rubio, Eddie A. James, Izortze Santín

This study identifies lncRNA-derived peptides that act as autoantigens in type 1 diabetes by activating CD4+ T cells through HLA-II restricted epitopes.

bioRxiv · Dec 2, 2025 · PreprintImmunology

m6A methylated long noncoding RNA regulates proinflammatory response emerging as novel target for IBD

Ane Olazagoitia‐Garmendia, Henar Rojas Márquez, Maialen Sebastian‐delaCruz, Aloña Agirre Lizaso, Anne Ochoa, Luis Manuel Mendoza, Maria Jesus Perugorria, Luís Bujanda, Alain Huerta Madrigal, Izortze Santín, Ainara Castellanos–Rubio

The paper identifies LOC339803 lncRNA as a mediator of intestinal inflammation through m6A methylation and YTHDC1 interaction, suggesting it as a potential therapeutic target for IBD.

Advanced Science · Jan 25, 2024Peer-reviewedMolecular Biology

Functional evolutionary convergence of long noncoding RNAs involved in embryonic development.

Ane Olazagoitia‐Garmendia, Rodrigo Senovilla-Ganzo, Fernando García‐Moreno, Ainara Castellanos–Rubio

The paper identifies functionally conserved non-homologous lncRNAs across species using k-mer content and structural analysis, validated through CRISPR Display in human and chicken cells.

Communications Biology · Sep 5, 2023Peer-reviewedMolecular Biology