ImmunologyThe Journal of Experimental MedicinePeer-reviewed
Intestinal cDC1s provide IL-12 dependent and independent functions required for CD4+ T cell mediated resistance to Cryptosporidium
Ian S. Cohn, Bethan A. Wallbank, Breanne E. Haskins…·Christopher A. Hunter
The paper investigates the role of intestinal cDC1s in CD4+ T cell-mediated resistance to Cryptosporidium, showing they support T cell expansion and effector function through IL-12-dependent and -independent mechanisms.