Author

Thomas John Jackson

Great Ormond Street HospitalORCID 0000-0003-1669-6666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Assay:proteomics· 1

Frequent Co-Authors

Courtney HimsworthiD· 2 shared John AndersoniD· 2 shared Louis ChesleriD· 2 shared Sophie Munnings-Tomes· 2 shared Amy K Erbe-Gurel· 1 shared Amy K. ErbeiD· 1 shared Chantelle E BowersiD· 1 shared Elizabeth Tucker· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Courtney HimsworthORCID

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2 papers

Recent·Most cited

ImmunologyPLoS ONEPeer-reviewedOct 27, 2026

CD47 blockade augments anti-GD2 driven phagocytosis in vitro but fails to improve in vivo efficacy in immune competent, chemoresistant neuroblastoma preclinical models

Courtney Himsworth, Thomas John Jackson, Chantelle E Bowers…·John Anderson

This study shows CD47 blockade enhances anti-GD2 phagocytosis in vitro but does not improve in vivo efficacy in neuroblastoma models.

DOI 10.1371/journal.pone.0353900

mouseproteomics

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Molecular BiologybioRxivPreprintNov 29, 2025

An optimised method for generation of murine CAR-T cells by CRISPR/Cas9.

Thomas John Jackson, Courtney Himsworth, Sophie Munnings-Tomes…·John Anderson

This paper optimizes CRISPR/Cas9 AAV transduction for generating murine CAR-T cells with high efficiency and minimal toxicity, enabling in vivo persistence and pre-clinical testing.

DOI 10.1101/2025.11.29.689298

mouseCRISPR screen

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