Giorgia Scarpellino

This study shows breast cancer-derived extracellular vesicles transfer P2X7 signaling competence to endothelial cells, enhancing anti-migratory and anti-tubulogenic effects through P2X7 sensitization.

This paper identifies an integrin-centered membrane complex in breast cancer cells that regulates f-actin organization and migration through ion transport proteins, with implications for therapeutic targeting of triple-negative breast cancer.

The paper introduces a database and pipeline to analyze transportome dysregulation in cancer, finding shared dysregulation patterns across cancer types.

BioTEA is a containerized R/Bioconductor-based tool for differential expression analysis of microarray data, offering reproducibility and flexibility through customizable pipelines.