Author

Michael R. Ehrenstein

University College HospitalORCID 0000-0003-1673-743XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Christopher R. JohniD· 1 shared Claire BeesleyiD· 1 shared Costantino PitzalisiD· 1 shared Daniel McClusky· 1 shared David WatsoniD· 1 shared Derek William GilroyiD· 1 shared Dominic RussiD· 1 shared Katriona GoldmanniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Christopher R. JohnORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 14, 2026

Elevated ferritin as a companion biomarker of myeloid-driven inflammation in RNP/Sm co-positive, treatment-resistant SLE endotype

Muhammad Ruhul Amin Shipa, Claire Beesley, Daniel McClusky…·Michael R. Ehrenstein

This paper identifies an RNP/Sm co-positive SLE endotype with myeloid-driven inflammation, hyperferritinaemia, and treatment resistance, suggesting targeted therapies are needed.

DOI 10.64898/2026.02.12.705402

humanproteomics

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BioinformaticsScientific ReportsPeer-reviewedFeb 4, 2020

M3C: A Monte Carlo reference-based consensus clustering algorithm

Christopher R. John, David Watson, Dominic Russ…·Michael R. Barnes

M3C improves consensus clustering by simulating null distributions to reduce bias and false positives in determining the number of clusters.

159 citationstop 2%

humanbulk RNA-seq

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