Yamile Márquez

The paper compares tissue-specific alternative splicing and gene expression across species to show they follow distinct evolutionary routes in repurposing ancestral genes, with TS-AS playing a key role in nervous system diversification.

This study identifies At-RS31 as a plant-specific splicing factor that regulates alternative splicing and integrates TOR and ABA signaling pathways through its binding targets and interactions with other splicing factors.

The paper investigates the evolution of tissue-specific gene expression across vertebrates and insects, finding that nearly half of ancestral genes have been recruited into tissue-specific transcriptomes.

ExOrthist infers exon orthologies across species by analyzing exon sequences and their surrounding intron context, enabling analysis at any evolutionary distance.

The paper decodes the compact genome of Dimorphilus gyrociliatus, revealing a conservative route to genome compaction with features similar to vertebrates.

The paper identifies HD-specific mis-splicing using intersect-RNA-seq in human and mouse models, revealing pathogenic splicing factors and effector genes.