GeneticsHuman Molecular GeneticsPeer-reviewed
A humanized yeast model reveals dominant-negative properties of neuropathy-associated alanyl-tRNA synthetase mutations
Rebecca Meyer‐Schuman, Sheila Marte, Tyler J. Smith…·Anthony Antonellis
The paper demonstrates that neuropathy-associated AARS1 mutations exhibit dominant-negative effects by reducing yeast growth when co-expressed with wild-type AARS1.
11 citations