Thomas Nowak

The paper develops a mathematical framework using CTMCs and quasi-stationary distributions to analyze stochastic behavior in multi-stable gene regulatory networks, providing design principles for toggle switches.

The paper introduces a unified SDE framework for efficient stochastic transcription trace generation, showing high accuracy with reduced computational cost.

This paper develops a phage-mediated CRISPRi system for intercellular communication in bacterial consortia, enabling multicellular logic gates with up to 7 cells and 3 inputs.

This paper presents a distributed algorithm for microbial whole-cell sensors inspired by the Allee effect, showing it works correctly in noisy environments through mathematical analysis and simulations.

The paper develops a synthetic communication system using phage M13 to study genetic exchange in E. coli and discovers an extracellular immunity factor that reduces infection rates by 70%.

MobsPy simplifies defining chemical reaction networks using meta-species, enabling easier modeling and simulation of biochemical systems.