Josepmaria Argemí

This study identifies ATF4 as a key driver of immune evasion in β-catenin-driven hepatocellular carcinoma by programming a proline-dependent metabolic axis that suppresses anti-tumor immunity.

This study shows that inhibiting G9a enhances the effectiveness of immune checkpoint inhibitors in hepatocellular carcinoma by improving tumor immunogenicity and T cell infiltration.

This study shows that Calpain-4 knockdown reduces cholesterol levels and relocalizes LXRα to the nucleus in alcohol-related liver disease.

The paper analyzes transcriptome diversity in alcohol-related liver disease to identify novel pathways and genes not detected by differential expression analysis.

JIND improves automated cell-type annotation in single-cell RNA-seq by learning a latent space for reliable classification and batch alignment without retraining.