Author

Yichang Chen

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0003-1697-3256Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:CITE-seq· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:multiple species· 1 Assay:protein sequence· 1

Frequent Co-Authors

Feng ZhuiD· 2 shared Zhan Mei ZhouiD· 2 shared Edward Charles HolmesiD· 1 shared Gang PaniD· 1 shared Jieping YeiD· 1 shared Jingcheng WuiD· 1 shared Jun LiiD· 1 shared M. WeiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioinformatics

Feng ZhuORCID

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2 papers

Recent·Most cited

BioinformaticsNature Machine IntelligencePeer-reviewedJun 18, 2025

Generalized Biological Foundation Model with Unified Nucleic Acid and Protein Language

Yong He, Pan Fang, Yongtao Shan…·Zhaorong Li

This paper introduces LucaOne, a foundation model trained on nucleic acid and protein sequences, demonstrating understanding of biological principles and performing well on related tasks.

55 citationstop 1%

multiple speciesDNA methylation

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ImmunologyGenomics Proteomics & BioinformaticsPeer-reviewedApr 21, 2025

TRAIT: A Comprehensive Database for T-cell Receptor-Antigen Interactions

M. Wei, Jingcheng Wu, Shuxian Bai…·Zhan Mei Zhou

TRAIT compiles nearly 8 million experimentally validated TCR-antigen pairs to provide a comprehensive resource for T-cell receptor interactions, aiding immunotherapy and vaccine design.

12 citationstop 4%

humanCITE-seq

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