Pan Fang

LucaPhylo infers phylogenetic trees from unaligned protein sequences using hyperbolic geometry and protein language models, achieving accuracy comparable to alignment-based methods for divergent RNA viruses.

This paper introduces LucaOne, a foundation model trained on nucleic acid and protein sequences, demonstrating understanding of biological principles and performing well on related tasks.

This paper introduces FluAdaX, a deep learning framework to predict influenza A virus cross-species transmission potential using genomic data, identifying key genes and variants associated with host adaptation.

AnnoPRO improves protein function annotation by using image-like representations and multimodal deep learning, showing better performance for rare protein families.