Jun Li

This study shows that repeated NGF injections into mouse knees cause multiple OA-like features without cartilage damage.

This paper presents a near-complete lamprey genome assembly, revealing gene family expansions and regulatory elements linked to vertebrate innovations.

This paper introduces LucaOne, a foundation model trained on nucleic acid and protein sequences, demonstrating understanding of biological principles and performing well on related tasks.

This study presents a chromosome-scale genome assembly and annotation of Alopecurus aequalis, revealing its genetic similarity to barley and expansion of herbicide resistance genes.

This study introduces Prognosis Consistency Scoring (PCS) to improve drug repurposing by addressing inconsistencies in gene prognosis between tumor and normal tissues, showing better performance than traditional DEG-based methods.

A single intravenous dose of AAV9-hGAA gene therapy improved motor milestones and GAA enzyme activity in an infant with infantile-onset Pompe disease.

This study identifies temporal gene expression patterns and regulatory pathways in mouse inner ear development using bulk RNA-Seq from E11.5 to P7.

The paper reports RNA 3D structure prediction results for SARS-CoV-2 5'- and 3'-UTRs using computational methods and expert analysis.

The paper assembles a high-quality Tibetan genome and identifies structural variants linked to high altitude adaptation and archaic hominid ancestry.