Lu Li

This study identifies HSD11B1 as a direct target of magnesium isoglycyrrhizinate, revealing its therapeutic mechanism in alcohol-associated liver disease through the HSD11B1-SREBP2-IDI1 signaling axis.

This paper identifies CTHRC1 as a therapeutic target and serum biomarker for aortic dissection, showing it regulates VSMC phenotype and aortic integrity via the ERK1/2 pathway.

DPHL v2 improves upon DPHL v1 by including semi-tryptic peptides and protein isoforms, increasing identified and dysregulated proteins in colorectal cancer analysis.