Alvaro A. Martinez

This study identifies IRAK1 as a chemoresistance factor in neuroblastoma and shows synergy between IRAK1 inhibition and various drugs in preclinical models.

The paper develops an AI algorithm using UMAP to classify bone marrow cells in B-ALL patients, improving disease prognosis and therapy decisions by identifying key subpopulations.

This paper introduces a stochastic mesoscopic simulation framework to model tumor heterogeneity and evolutionary dynamics while maintaining low computational costs.