Author

Marion Le Grand

Centre National de la Recherche ScientifiqueORCID 0000-0002-4910-1289Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Eddy PasquieriD· 3 shared Kévin MülleriD· 2 shared Alexandra BomaneiD· 1 shared Alison M. FergusoniD· 1 shared Alvaro A. MartineziD· 1 shared Annael BerniniiD· 1 shared Anne BéghiniD· 1 shared Baptiste MouyssetiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersCancer Biology

Eddy PasquierORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 16, 2026

Microdomes: Micro-engineered Microdome arrays enable standardised and shear-free 3D biology with full-spectrum optical imaging compatibility

Mei Shan Cheam, Saburnisha Binte Mohamad Raffi, Hui Ting Ong…·Anne Béghin

The paper introduces Microdomes, a 3D biology platform that enables shear-free handling and full-spectrum optical imaging of spheroids and organoids.

DOI 10.64898/2026.09.10.750786

organoid / primary cultureexperimental assay

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Cancer BiologybioRxivPreprintJul 25, 2026

Deletion of Ferritin Heavy Chain Limits Tumor Growth and Promotes Iron-Dependent Stress in Medulloblastoma

Fabien Segui, Jérôme Durivault, Marina Pagnuzzi…·Vincent Picco

This study shows that deleting ferritin heavy chain in medulloblastoma cells limits tumor growth by promoting iron-dependent stress and sensitizing cells to iron toxicity.

DOI 10.64898/2026.07.23.739635

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintJan 9, 2026

Reverse molecular pharmacology identifies the non-canonical axis of IRAK as a chemoresistance factor in neuroblastoma

Marion Le Grand, Chen Buxbaum, Mathilde Kerhervé…·Eddy Pasquier

This study identifies IRAK1 as a chemoresistance factor in neuroblastoma and shows synergy between IRAK1 inhibition and various drugs in preclinical models.

DOI 10.64898/2026.01.09.697473

humanbulk RNA-seq

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