ImmunologyCell Communication and SignalingPeer-reviewed
IL-35 produced by dendritic cells via TIM-3-STAT3 signaling contributes to the development of visceral leishmaniasis
Sandeep Kumar, Shubham, Manish Mishra…·Pradip Sen
This study identifies the TIM-3-STAT3-IL-35 axis in dendritic cells as a driver of immunosuppression in visceral leishmaniasis, showing that STAT3 inhibition reduces disease severity.
DOI 10.1186/s12964-026-03227-x