Steven E. Finkel

This study benchmarks a novel qPCR-based microbiome profiling platform against 16S amplicon and metagenomic sequencing methods, showing qPCR's superior accuracy and sensitivity for species-level detection.

This study shows that a glucose-fed microbiota in C. elegans reduces lifespan and healthspan, increases intestinal permeability, and raises susceptibility to bacterial pathogens.

This study shows that E. coli processing of glucose reduces C. elegans lifespan and healthspan by increasing oxidative stress and decreasing detoxification gene expression.