Author

Anna Luisa Di Stefano

Ospedale di LivornoORCID 0000-0003-1746-0647Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:large language model· 1

Frequent Co-Authors

Chiara Maria MazzantiiD· 2 shared Francesca LessiiD· 2 shared Francesco PasqualettiiD· 2 shared Mariangela MorelliiD· 2 shared Orazio Santo SantonocitoiD· 2 shared Paolo AretiniiD· 2 shared Sara FranceschiiD· 2 shared Aldo Pastore· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCancer Biology

Chiara Maria MazzantiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 20, 2026

From Single-Cell Emergent Behaviors to Clinical Outcome: PTEN-driven Migratory Efficiency as a Potential New Vulnerability in Glioblastoma

Mariangela Morelli, Gianmarco Ferri, Francesca Lessi…·Chiara Maria Mazzanti

This study identifies PTEN gain-of-function mutations as linked to increased migratory efficiency in glioblastoma cells, correlating with poorer patient survival.

DOI 10.64898/2026.03.18.712310

humanbulk RNA-seq

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BioinformaticsNature CommunicationsPeer-reviewedFeb 14, 2025

Learning and actioning general principles of cancer cell drug sensitivity

Francesco Carli, Pierluigi Di Chiaro, Mariangela Morelli…·Francesco Raimondi

The paper develops interpretable models to predict cancer drug sensitivity using transcriptomics data and enhances predictions with large language models, validated on clinical samples.

38 citationstop 1%

humanbulk RNA-seq

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