Gianmarco Ferri

Expansion microscopy reveals insulin granule clustering in human β-cells in type 2 diabetes

This study uses expansion microscopy to analyze insulin granule organization in human β-cells, finding increased clustering in type 2 diabetes without significant granule depletion.

From Single-Cell Emergent Behaviors to Clinical Outcome: PTEN-driven Migratory Efficiency as a Potential New Vulnerability in Glioblastoma

This study identifies PTEN gain-of-function mutations as linked to increased migratory efficiency in glioblastoma cells, correlating with poorer patient survival.

Metabolic-imaging of human glioblastoma explants: a new precision-medicine model to predict tumor treatment response early

This paper develops a functional precision medicine approach using metabolic imaging to predict glioblastoma treatment response early in ex-vivo organoids, identifying responder and non-responder groups and a new molecular signature.