Genetic & Genomic MedicinemedRxivPreprint
Pathway-based polygenic risk scores for schizophrenia and associations with clinical and neuroimaging phenotypes in UK Biobank
Miruna C. Barbu, Gladi Thng, Mark J. Adams…·Heather Clare Whalley
This study calculates pathway-based polygenic risk scores for schizophrenia using gene-sets related to synaptic function and histone modification, and finds associations with neuroimaging and clinical traits in UK Biobank.