Author
Brigham and Women's HospitalORCID 0000-0003-1768-6777Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Harlan P. Stevens, Ali Doğa Yücel, Russell A. Gould…·George McDonald Church
The paper analyzes single-cell multiome data from human HSPCs to show aging-related rewiring of gene regulatory networks, leading to stress hyperactivation, myeloid bias, and identity loss.
Ali Doğa Yücel, Harlan P. Stevens, Alexander Tyshkovskiy, Vadim N. Gladyshev
The paper identifies conserved master regulators that coordinate reprogramming-induced rejuvenation across different cell types and shows that perturbing these regulators can modulate transcriptomic age.
Harlan P. Stevens, Carly V Winegar, Arwen F Oakley, Stephen Piccolo
The paper evaluates color accessibility of scientific images for deuteranopes, finds 12.8% are problematic, and develops a tool to identify and simulate these issues.