Irene Frigerio

The paper quantifies regional synaptic degeneration in Parkinson's Disease and Dementia with Lewy bodies, linking it to alpha-synuclein burden, axonal damage, and clinical outcomes.

This study uses diffusion MRI and histopathology to show that microstructural changes in the substantia nigra and its tracts in Parkinson's disease correlate with dopaminergic loss and Lewy neurite pathology.

This study examines the regional distribution of neurofilaments in Parkinson's disease and its association with pathological markers and MRI measures of brain atrophy and diffusivity.

The paper examines how structural connectivity changes relate to cholinergic cell density in the nucleus basalis of Meynert in Alzheimer's disease, finding specific associations in amnestic cases.

This study identifies histopathological correlates of MRI cortical atrophy in Alzheimer's disease, finding that phosphorylated-tau and reactive microglia loads strongly correlate with atrophy in specific brain regions.