Thomas Dupic

This study maps epistatic interactions in Omicron SARS-CoV-2 Spike RBD mutations, revealing how mutations interact to affect ACE2 binding and antibody evasion.

This study compares adaptive routes in two yeast species after 10,000 generations, finding parallel but distinct molecular mechanisms of adaptation.

This study presents a computational method to identify antigen-specific BCRs from immune repertoires using sequence similarity and validates it with human data post-vaccination and infection.

The paper shows that reference-free analysis is equivalent to reference-based methods, leading to identical landscapes but different interpretations of epistasis.

This study demonstrates that immune repertoires can uniquely identify individuals with high accuracy using a classifier based on repertoire similarity.