The Role of Macronutrient Composition in Semipurified Diets in Shaping Distinct Obesity Phenotypes: Evidence for Hepatic Oxidative Stress Involvement
Pedro Rocha Tenório, Gabriel Smolak Sobieski e Silva, Isadora Chagas Vercellone, Débora Hipólito Quadreli, J. de Castro, Glaura Scantamburlo Alves Fernandes, Fábio Goulart de Andrade
This study compares the effects of different diets on obesity and metabolic health in rats, finding that high-fat/high-sugar diets cause distinct metabolic dysfunction and hepatic oxidative stress.
bioRxiv · Jul 17, 2025 · PreprintPhysiology