Author

David L. Donoho

Cold Spring Harbor LaboratoryORCID 0000-0003-1830-710XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:batch correction / integration· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Rong MaiD· 2 shared Arvind RishiiD· 1 shared Craig Podszus· 1 shared Dan LevyiD· 1 shared Daniel Bradford· 1 shared Danielle Stauder· 1 shared Elizabeth Rose· 1 shared Eric SuniD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Rong MaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

DNA and RNA from the same single nucleus reveals interactions between genomic and transcriptomic landscapes in human tumor samples

Siran Li, Joan Alexander, Jude Kendall, Peter Andrews, Elizabeth Rose, Hope Orjuela, Sarah Park, Craig Podszus, Liam Shanley, Nissim Ranade, Patrick Morris, Danielle Stauder, Daniel Bradford, Michael Ronemus, Arvind Rishi, , Dan Levy

This study introduces hybrid BAG-seq to analyze DNA and RNA from single nuclei in tumor samples, revealing genome-transcriptome interactions and tumor heterogeneity.

bioRxiv · Oct 4, 2023 · PreprintGenomics

Is your data alignable? Principled and interpretable alignability testing and integration of single-cell data

Rong Ma, Eric Sun, David L. Donoho, James Zou

This paper introduces SMAI, a framework for alignability testing and integration of single-cell data, showing it outperforms existing methods and improves downstream analyses.

bioRxiv · Aug 3, 2023 · PreprintBioinformatics