Author
Yale UniversityORCID 0000-0003-1839-5912Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Shuozhen Bao, Gretchen Long, Shouryo Ghose…·Rong Fan
This paper uses surprisal information-theoretic analysis on spatial transcriptomic data from human glioblastoma to uncover hidden spatial programs and interactions not detected by standard methods.
Danielle F. Miyagishima, Arman Afrasiyabi, Declan McGuone…·Murat Günel
This study identifies multicellular spatial molecular programs in meningiomas using multi-omic data and develops a model to infer these programs from histopathology.
Sattar Khoshkhoo, Mingyun Bae, Yilan Wang…·Christopher A. Walsh
This study identifies somatic Ras-MAPK pathway variants in hippocampal tissue from patients with drug-resistant epilepsy, showing their association with clonal competition and worse surgical outcomes.
Tamrin Chowdhury, C. Mircea S. Tesileanu, Emre Kocakavuk…·Roel G.W. Verhaak
This study identifies genetic changes in IDH-mutant gliomas that correlate with treatment response and tumor evolution using longitudinal genomic data from 206 patient samples.
Shujuan Zhao, Kedous Y. Mekbib, Martijn A. van der Ent…·Kristopher Thomas Kahle
The paper identifies genetic variants in RASA1 and EPHB4 associated with vein of Galen malformations through exome analysis and single-cell transcriptomics.
Manik Razdan Kuchroo, Danielle F. Miyagishima, Holly R. Steach…·Smita Krishnaswamy
The paper introduces spARC, a method to recover spatial signaling networks in gliomas, revealing an Osteopontin-CD44 interaction enriched in grade IV astrocytomas.