Eshna Jash

This study identifies additional roles of the C. elegans sex-1 gene in regulating sex determination and dosage compensation beyond its known repression of xol-1.

This study investigates the transcriptional effects of disrupting nuclear RNAi in C. elegans, showing that while X chromosome decondensation occurs, global transcriptional de-repression is not observed, and HRDE-1 and NRDE-3 regulate their targets through distinct mechanisms.

The paper shows that condensin IDC is required to maintain X chromosome repression in C. elegans larvae and adults, but not during embryogenesis.

This study shows XOL-1 regulates developmental timing and dosage compensation in C. elegans hermaphrodite embryos by modulating the H3K9 methylation landscape.

This study identifies nuclear Argonaute genes involved in dosage compensation in C. elegans, showing they regulate X chromosome condensation independently of xol-1.