NeuroscienceNeurobiology of DiseasePeer-reviewed
PYK2 in the dorsal striatum of Huntington disease R6/2 mouse model
Omar Al–Massadi, Mélody Labarchède, Benoit de Pins…·Jean‐Antoine Girault
This study examines PYK2 levels and effects of its restoration in the striatum of HD mouse models and human patients, finding reduced levels but only partial improvement in motor phenotypes.
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