Pragati Kore

FELIX improves genetic association analysis by accounting for local ancestry in admixed populations, increasing significant loci and improving polygenic score prediction.

Tractor-Burden improves gene discovery in admixed populations by incorporating local ancestry in rare variant burden testing, identifying additional genes and pathways for type 2 diabetes.

This paper improves allele frequency estimates in gnomAD by applying local ancestry inference to admixed populations, revealing significant frequency differences that could affect clinical interpretation.

This study shows prenatal exposure to EDCs disrupts and reconstitutes gene-behavior relationships in adult rat brain regions involved in social behavior.

This study shows that C. elegans can model AD-related neurodegeneration, demonstrating that APOE4 exacerbates APP-induced cholinergic neurodegeneration.