Author

Emily A. King

AbbVie (United States)ORCID 0000-0003-1877-8673Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:GWAS summary statistics· 3 Organism:human· 3 Research Focus:GWAS / association mapping· 2 Approach:Bayesian inference· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Jacob F. DegneriD· 3 shared J. Wade DavisiD· 2 shared Adriana Donovan· 1 shared Bridget M. Riley-GillisiD· 1 shared Chen WengiD· 1 shared Christopher RouyaiD· 1 shared Eladio Marquez· 1 shared Fengjiao Dunbar· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Jacob F. DegnerORCID

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4 papers

Recent·Most cited

GenomicsbioRxivPreprintFeb 18, 2026

Modeling mitochondrial inheritance enables high-precision single-cell lineage tracing in humans

Teng Fei Gao, Chen Weng, Isaac Johnson…·Vijay G. Sankaran

MitoDrift models mitochondrial inheritance to enable high-precision lineage tracing in human tissues, revealing clonal dynamics and linking them to transcriptional and epigenetic programs.

2 citations

humanbulk RNA-seq

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Genetic & Genomic MedicinemedRxivPreprintSep 5, 2024

Integration of GWAS and multi-omic QTLs identifies uncharacterized COVID-19 gene-biotype and phenotype associations

Meritxell Oliva, Emily A. King, Reza K. Hammond…·Jacob F. Degner

The paper integrates GWAS and multi-omic QTLs to identify gene-biotype and phenotype associations related to COVID-19, revealing pleiotropy and causal links.

DOI 10.1101/2024.09.05.24313137

humanGWAS summary statistics

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BioinformaticsBMC BioinformaticsPeer-reviewedMay 17, 2021

Estimating colocalization probability from limited summary statistics

Emily A. King, Fengjiao Dunbar, J. Wade Davis, Jacob F. Degner

The paper introduces POEMColoc, a method to estimate colocalization probability using limited summary statistics, and finds evidence for colocalization between 150,000 trait-gene-tissue triplets.

13 citations

GWAS summary statisticsstatistical model

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GeneticsPLoS GeneticsPeer-reviewedDec 12, 2019

✦ In-depth digest

Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval.

Emily A. King, J. Wade Davis, Jacob F. Degner

Updated pipeline and genetic data confirm genetically supported drug targets succeed more often; Mendelian (OMIM) support replicates prospectively, while GWAS support is weaker unless coding-linked.

649 citationstop 1%

humanGWAS summary statistics

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